23S rRNK (citozin1962-C5)-metiltransferaza
(Preusmjereno sa stranice RlmI)
| 23S rRNK (citozin1962-C5)-metiltransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.1.1.191 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
23S rRNK (citozin1962-C5)-metiltransferaza (EC 2.1.1.191, RlmI, metiltransferaza I velike podjedinice rRNK, YccW) je enzim sa sistematskim imenom S-adenozil-L-metionin:23S rRNK (citozin1962-C5)-metiltransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- S-adenozil-L-metionin + citozin1962 u 23S rRNK S-adenozil-L-homocistein + 5-metilcitozin1962 u 23S rRNK
Ovaj enzim specifično metiliše citozin1962 u C5 poziciji 23S rRNK.
Reference[uredi | uredi kod]
- ↑ Purta, E., O'Connor, M., Bujnicki, J.M. and Douthwaite, S. (2008). „YccW is the m5C methyltransferase specific for 23S rRNA nucleotide 1962”. J. Mol. Biol. 383: 641-651. PMID 18786544.
- ↑ Sunita, S., Tkaczuk, K.L., Purta, E., Kasprzak, J.M., Douthwaite, S., Bujnicki, J.M. and Sivaraman, J. (2008). „Crystal structure of the Escherichia coli 23S rRNA:m5C methyltransferase RlmI (YccW) reveals evolutionary links between RNA modification enzymes”. J. Mol. Biol. 383: 652-666. PMID 18789337.
Literatura[uredi | uredi kod]
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- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
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- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.