Crveni hlorofil katabolit reduktaza
(Preusmjereno sa stranice RCC reduktaza)
| Crveni hlorofil katabolit reduktaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.3.1.80 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Crveni hlorofil katabolit reduktaza (EC 1.3.1.80, RCCR, RCC reduktaza, red Chl katabolitna reduktaza) je enzim sa sistematskim imenom primarni fluorscentni hlorofilni katabolit:NADP+ oksidoreduktaza.[1][2][3][4][5] Ovaj enzim katalizuje sledeću hemijsku reakciju
- primarni fluorscent hlorofil katabolit + NADP+ red hlorofil katabolit + NADPH + H+
Degradacija hlorofila je karakteristični simptom starenja lišća i sazrevanja voća. Za reakciju koju katalizuje ovaj enzim neophodan je redukovani feredoksin, koji se formira bilo putem NADPH u putu pentoznog-fosfata ili dejstvom fotosistema I. Ova reakcija se odvija bez otpuštanja supstrata iz EC 1.14.12.20, feoforbid a oksigenaze.
- ↑ Rodoni, S., Mühlecker, W., Anderl, M., Kräutler, B., Moser, D., Thomas, H., Matile, P. and Hörtensteiner, S. (1997). „Chlorophyll breakdown in senescent chloroplasts. Cleavage of pheophorbide a in two enzymic steps”. Plant Physiol. 115: 669-676. PMID 12223835.
- ↑ Wüthrich, K.L., Bovet, L., Hunziker, P.E., Donnison, I.S. and Hörtensteiner, S. (2000). „Molecular cloning, functional expression and characterisation of RCC reductase involved in chlorophyll catabolism”. Plant J. 21: 189-198. PMID 10743659.
- ↑ Pružinská, A., Anders, I., Aubry, S., Schenk, N., Tapernoux-Lüthi, E., Müller, T., Kräutler, B. and Hörtensteiner, S. (2007). „In vivo participation of red chlorophyll catabolite reductase in chlorophyll breakdown”. Plant Cell 19: 369-387. PMID 17237353.
- ↑ Hörtensteiner, S. (2006). „Chlorophyll degradation during senescence”. Annu. Rev. Plant Biol. 57: 55-77. PMID 16669755.
- ↑ Rodoni, S., Vicentini, F., Schellenberg, M., Matile, P. and Hörtensteiner, S. (1997). „Partial purification and characterization of red chlorophyll catabolite reductase, a stroma protein involved in chlorophyll breakdown”. Plant Physiol. 115: 677-682. PMID 12223836.
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.