5-nitrosalicilat dioksigenaza
(Preusmjereno sa stranice NaaB (gen))
| 5-nitrosalicilat dioksigenaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.13.11.64 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
5-nitrosalicilat dioksigenaza (EC 1.13.11.64, naaB (gen)) je enzim sa sistematskim imenom 5-nitrosalicilat:kiseonik 1,2-oksidoreduktaza (deciklizacija).[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- 5-nitrosalicilat + O2 2-okso-3-(5-oksofuran-2-iliden)propanoat + nitrit (sveukupna reakcija)
- (1a) 5-nitrosalicilat + O2 4-nitro-6-oksohepta-2,4-dienedioat
- (1b) 4-nitro-6-oksohepta-2,4-dienedioat 2-okso-3-(5-oksofuran-2-iliden)propanoat + nitrit (spontana reakcija)
Enzim bakterija iz zemljišta Bradyrhizobium sp. JS329 učestvujeu u degradaciji 5-nitroantranilata.
Reference[uredi | uredi kod]
- ↑ Qu, Y. and Spain, J.C. (2010). „Biodegradation of 5-nitroanthranilic acid by Bradyrhizobium sp. strain JS329”. Appl. Environ. Microbiol. 76: 1417-1422. PMID 20081004.
- ↑ Qu, Y. and Spain, J.C. (2011). „Molecular and biochemical characterization of the 5-nitroanthranilic acid degradation pathway in Bradyrhizobium sp. strain JS329”. J. Bacteriol. 193: 3057-3063. PMID 21498645.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.