23S rRNK (adenin1618-N6)-metiltransferaza
(Preusmjereno sa stranice M6A1618 methyltransferase)
| 23S rRNK (adenin1618-N6)-metiltransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.1.1.181 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
23S rRNK (adenin1618-N6)-metiltransferaza (EC 2.1.1.181, metiltransferaza F velike podjedinice rRNK, YbiN protein, rlmF (gen), m6A1618 metiltransferaza) je enzim sa sistematskim imenom S-adenozil-L-metionin:23S rRNK (adenin1618-N6)-metiltransferaza.[1] Ovaj enzim katalizuje sledeću hemijsku reakciju
- S-adenozil-L-metionin + adenin1618 u 23S rRNK S-adenozil-L-homocistein + N6-metiladenin1618 u 23S rRNK
Rekombinantni YbiN protein ima sposobnost metilacije parcijalno deprotonisane 50 S ribozomalne podjedinice. On ne deluje na kompletno formirane 50 S podjednice, niti na kompletno deprotonisanu 23 S rRNK.
- ↑ Sergiev, P.V., Serebryakova, M.V., Bogdanov, A.A. and Dontsova, O.A. (2008). „The ybiN gene of Escherichia coli encodes adenine-N6 methyltransferase specific for modification of A1618 of 23 S ribosomal RNA, a methylated residue located close to the ribosomal exit tunnel”. J. Mol. Biol. 375: 291-300. PMID 18021804.
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