Linoleat 9S-lipoksigenaza
(Preusmjereno sa stranice LOX1 (gene name))
| Linoleat 9S-lipoksigenaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.13.11.58 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Linoleat 9S-lipoksigenaza (EC 1.13.11.58, 9-lipoksigenaza, 9S-lipoksigenaza, linoleatna 9-lipoksigenaza, LOX1 (gen), 9S-LOX) je enzim sa sistematskim imenom linoleat:kiseonik 9S-oksidoreduktaza.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
- linoleat + O2 (9S,10E,12Z)-9-hidroperoksi-10,12-oktadekadienoat
Ovaj enzim sadrži gvožđe nevezano za hem.
Reference[uredi | uredi kod]
- ↑ Vellosillo, T., Martinez, M., Lopez, M.A., Vicente, J., Cascon, T., Dolan, L., Hamberg, M. and Castresana, C. (2007). „Oxylipins produced by the 9-lipoxygenase pathway in Arabidopsis regulate lateral root development and defense responses through a specific signaling cascade”. Plant Cell 19: 831-846. PMID 17369372.
- ↑ Boeglin, W.E., Itoh, A., Zheng, Y., Coffa, G., Howe, G.A. and Brash, A.R. (2008). „Investigation of substrate binding and product stereochemistry issues in two linoleate 9-lipoxygenases”. Lipids 43: 979-987. PMID 18795358.
- ↑ Andreou, A.Z., Hornung, E., Kunze, S., Rosahl, S. and Feussner, I. (2009). „On the substrate binding of linoleate 9-lipoxygenases”. Lipids 44: 207-215. PMID 19037675.
- ↑ Bannenberg, G., Martinez, M., Hamberg, M. and Castresana, C. (2009). „Diversity of the enzymatic activity in the lipoxygenase gene family of Arabidopsis thaliana”. Lipids 44: 85-95. PMID 18949503.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.