CDP-abekvoza sintaza
(Preusmjereno sa stranice EC 1.1.1.341)
| CDP-abekvoza sintaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.1.1.341 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
CDP-abekvoza sintaza (EC 1.1.1.341, rfbJ (gen)) je enzim sa sistematskim imenom CDP-alfa-D-abekvoza:NADP+ 4-oksidoreduktaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- CDP-alfa-D-abekvoza + NADP+ CDP-4-dehidro-3,6-didezoksi-alfa-D-glukoza + NADPH + H+
Ovaj enzim je izolovan iz Yersinia pseudotuberculosis i Salmonella enterica.
Reference[uredi | uredi kod]
- ↑ Kessler, A.C., Brown, P.K., Romana, L.K. and Reeves, P.R. (1991). „Molecular cloning and genetic characterization of the rfb region from Yersinia pseudotuberculosis serogroup IIA, which determines the formation of the 3,6-dideoxyhexose abequose”. J. Gen. Microbiol. 137: 2689-2695. PMID 1724263.
- ↑ Wyk, P. and Reeves, P. (1989). „Identification and sequence of the gene for abequose synthase, which confers antigenic specificity on group B salmonellae: homology with galactose epimerase”. J. Bacteriol. 171: 5687-5693. PMID 2793832.
- ↑ Thorson, J.S., Lo, S.F., Ploux, O., He, X. and Liu, H.W. (1994). „Studies of the biosynthesis of 3,6-dideoxyhexoses: molecular cloning and characterization of the asc (ascarylose) region from Yersinia pseudotuberculosis serogroup VA”. J. Bacteriol. 176: 5483-5493. PMID 8071227.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.