Epoetin alfa
Izgled
(Preusmjereno sa stranice DB00016)
Klinički podaci | |
---|---|
Robne marke | Epogen, Epogen (Amgen Inc.), Epogin (Chugai), Epomax (Elanex) |
AHFS/Drugs.com | alfa.html Monografija |
Identifikatori | |
CAS broj | 113427-24-0 |
ATC kod | B03XA02 , B03XA01 |
DrugBank | DB00016 |
ChEMBL[1] | CHEMBL1201565 |
Hemijski podaci | |
Formula | C815H1317N233O241S5 |
Mol. masa | 18396.1 |
Fizički podaci | |
Tačka topljenja | 53 °C (127 °F) |
Farmakoinformacioni podaci | |
Trudnoća | ? |
Pravni status | |
Način primene | Subkutano, intravenozno |
Epoetin alfa (rINN) rekombinantni je ljudski eritropoietin, koji se proizvodi u CHO ćelijama.[2][3][4]
- ↑ Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). „ChEMBL: a large-scale bioactivity database for drug discovery”. Nucleic Acids Res 40 (Database issue): D1100-7. DOI:10.1093/nar/gkr777. PMID 21948594.
- ↑ Walsh G, Spada S (2005). „Epogen/Procrit”. Directory of approved biopharmaceutical products. Boca Raton: CRC Press. str. 39–41. ISBN 0-415-26368-9.
- ↑ Knox C, Law V, Jewison T, Liu P, Ly S, Frolkis A, Pon A, Banco K, Mak C, Neveu V, Djoumbou Y, Eisner R, Guo AC, Wishart DS (2011). „DrugBank 3.0: a comprehensive resource for omics research on drugs”. Nucleic Acids Res. 39 (Database issue): D1035-41. DOI:10.1093/nar/gkq1126. PMC 3013709. PMID 21059682.
- ↑ David S. Wishart, Craig Knox, An Chi Guo, Dean Cheng, Savita Shrivastava, Dan Tzur, Bijaya Gautam, and Murtaza Hassanali (2008). „DrugBank: a knowledgebase for drugs, drug actions and drug targets”. Nucleic Acids Res 36 (Database issue): D901-6. DOI:10.1093/nar/gkm958. PMC 2238889. PMID 18048412.
- Hardman JG, Limbird LE, Gilman AG. (2001). Goodman & Gilman's The Pharmacological Basis of Therapeutics (10 izd.). New York: McGraw-Hill. DOI:10.1036/0071422803. ISBN 0-07-135469-7.
- Thomas L. Lemke, David A. Williams, ur. (2007). Foye's Principles of Medicinal Chemistry (6 izd.). Baltimore: Lippincott Willams & Wilkins. ISBN 0-7817-6879-9.