Cu2+ eksportujuća ATPaza
(Preusmjereno sa stranice Cu2+-eksportujuća ATPaza)
| Cu2+ eksportujuća ATPaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.6.3.4 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Cu2+ eksportujuća ATPaza (EC 3.6.3.4, Cu2+-exporting ATPase) je enzim sa sistematskim imenom ATP fosfohidrolaza (Cu2+ eksport).[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
Ova P-tip ATPaza podleže kovalentnoj fosforilaciji tokom transportnog ciklusa.
Reference[uredi | uredi kod]
- ↑ Vulpe, C., Levinson, B., Whitney, S., Packman, S. and Gitschier, J. (1993). „Isolation of a candidate gene for Menkes disease and evidence that it encodes a copper-transporting ATPase”. Nat. Genet. 3: 7-13. PMID 8490659.
- ↑ Petrukhin, K., Lutsenko, S., Chernov, I., Ross, B.M., Kaplan, J.H. and Gilliam, T.C. (1994). „Characterization of the Wilson disease gene encoding a P-type copper-transporting ATPase: genomic organization, alternative splicing, and structure/function predictions”. Hum. Mol. Genet. 3: 1647-1656. PMID 7833924.
- ↑ Fagan, M.J. and Saier, M.H., Jr. (1994). „P-type ATPases of eukaryotes and bacteria: sequence analyses and construction of phylogenetic trees”. J. Mol. Evol. 38: 57-99. PMID 8151716.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.