Karlakton sintaza
(Preusmjereno sa stranice 9-cis-10'-apo-beta-carotenal:O2 oxidoreductase (14,15-cleaving, carlactone-forming))
| Karlakton sintaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.13.11.69 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Karlakton sintaza (EC 1.13.11.69, CCD8 (gen), MAX4 (gen), NCED8 (gen)) je enzim sa sistematskim imenom 9-cis-10'-apo-beta-karotenal:O2 oksidoreduktaza (14,15-razlaganje, karlakton).[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- 9-cis-10'-apo-beta-karotenal + 2 O2 karlakton + (2E,4E,6E)-7-hidroksi-4-metilhepta-2,4,6-trienal
Ovaj enzim sadrži Fe2+. On učestvuje u biosintezi strigolaktona, biljnih hormona.
Reference[uredi | uredi kod]
- ↑ Sorefan, K., Booker, J., Haurogne, K., Goussot, M., Bainbridge, K., Foo, E., Chatfield, S., Ward, S., Beveridge, C., Rameau, C. and Leyser, O. (2003). „MAX4 and RMS1 are orthologous dioxygenase-like genes that regulate shoot branching in Arabidopsis and pea”. Genes Dev. 17: 1469-1474. PMID 12815068.
- ↑ Schwartz, S.H., Qin, X. and Loewen, M.C. (2004). „The biochemical characterization of two carotenoid cleavage enzymes from Arabidopsis indicates that a carotenoid-derived compound inhibits lateral branching”. J. Biol. Chem. 279: 46940-46945. PMID 15342640.
- ↑ Alder, A., Jamil, M., Marzorati, M., Bruno, M., Vermathen, M., Bigler, P., Ghisla, S., Bouwmeester, H., Beyer, P. and Al-Babili, S. (2012). „The path from β-carotene to carlactone, a strigolactone-like plant hormone”. Science 335: 1348-1351. PMID 22422982.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.