8-Dimetilalilnaringenin 2'-hidroksilaza
| 8-Dimetilalilnaringenin 2'-hidroksilaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.14.13.103 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
8-Dimetilalilnaringenin 2'-hidroksilaza (EC 1.14.13.103, 8-DMAN 2'-hidroksilaza) je enzim sa sistematskim imenom soforaflavanon-B,NADPH:kiseonik oksidoreduktaza (2'-hidroksilacija).[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- soforaflavanon B + NADPH + H+ + O2 leahianon G + NADP+ + H2O
Ovaj za membranu vezani hem-tiolatni protein je asociran sa endoplazmičnim retikulumom. On je specifičan za soforaflavanon B kao supstrat. NADPH se ne može zameniti drugim kofaktorima.
- ↑ Yamamoto, H., Yatou, A. and Inoue, K. (2001). „8-Dimethylallylnaringenin 2′-hydroxylase, the crucial cytochrome P450 mono-oxygenase for lavandulylated flavanone formation in Sophora flavescens cultured cells”. Phytochemistry 58: 671-676. PMID 11672730.
- ↑ Zhao, P., Inoue, K., Kouno, I. and Yamamoto, H. (2003). „Characterization of leachianone G 2′′-dimethylallyltransferase, a novel prenyl side-chain elongation enzyme for the formation of the lavandulyl group of sophoraflavanone G in Sophora flavescens Ait. cell suspension cultures”. Plant Physiol. 133: 1306-1313. PMID 14551337.
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