6-Fosfo-3-heksuloizomeraza
(Preusmjereno sa stranice 6-fosfo-3-heksuloza izomeraza)
| 6-Fosfo-3-heksuloizomeraza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 5.3.1.27 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
6-Fosfo-3-heksuloizomeraza (EC 5.3.1.27, 3-heksuloza-6-fosfat izomeraza, fosfo-3-heksuloizomeraza, PHI, 6-fosfo-3-heksuloza izomeraza, YckF) je enzim sa sistematskim imenom D-arabino-heks-3-uloza-6-fosfat izomeraza.[1][2][3][4][5][6] Ovaj enzim katalizuje sledeću hemijsku reakciju
- D-arabino-heks-3-uloza 6-fosfat D-fruktoza 6-fosfat
Ovaj enzim učestvuje u ribuloza-monofosfatnom ciklusu formaldehidne fiksacije.
Reference[uredi | uredi kod]
- ↑ Ferenci, T., Strøm, T. and Quayle, J.R. (1974). „Purification and properties of 3-hexulose phosphate synthase and phospho-3-hexuloisomerase from Methylococcus capsulatus”. Biochem. J. 144: 477-486. PMID 4219834.
- ↑ Yurimoto, H., Kato, N. and Sakai, Y. (2005). „Assimilation, dissimilation, and detoxification of formaldehyde, a central metabolic intermediate of methylotrophic metabolism”. Chem. Rec. 5: 367-375. PMID 16278835.
- ↑ Kato, N., Yurimoto, H. and Thauer, R.K. (2006). „The physiological role of the ribulose monophosphate pathway in bacteria and archaea”. Biosci. Biotechnol. Biochem. 70: 10-21. PMID 16428816.
- ↑ Orita, I., Yurimoto, H., Hirai, R., Kawarabayasi, Y., Sakai, Y. and Kato, N. (2005). „The archaeon Pyrococcus horikoshii possesses a bifunctional enzyme for formaldehyde fixation via the ribulose monophosphate pathway”. J. Bacteriol. 187: 3636-3642. PMID 15901685.
- ↑ Martinez-Cruz, L.A., Dreyer, M.K., Boisvert, D.C., Yokota, H., Martinez-Chantar, M.L., Kim, R. and Kim, S.H. (2002). „Crystal structure of MJ1247 protein from M. jannaschii at 2.0 Å resolution infers a molecular function of 3-hexulose-6-phosphate isomerase”. Structure 10: 195-204. PMID 11839305.
- ↑ Taylor, E.J., Charnock, S.J., Colby, J., Davies, G.J. and Black, G.W. (2001). „Cloning, purification and characterization of the 6-phospho-3-hexulose isomerase YckF from Bacillus subtilis”. Acta Crystallogr. D Biol. Crystallogr. 57: 1138-1140. PMID 11468398.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.