(+)-Kamfor 6-ekso-hidroksilaza
(Preusmjereno sa stranice (+)-kamfor,NADPH:kiseonik oksidoreduktaza (6-ekso-hidroksilacija))
| (+)-Kamfor 6-ekso-hidroksilaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.14.13.161 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
(+)-Kamfor 6-ekso-hidroksilaza (EC 1.14.13.161, (+)-kamfor 6-hidroksilaza) je enzim sa sistematskim imenom (+)-kamfor,NADPH:kiseonik oksidoreduktaza (6-exo-hidroksilacija).[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- (+)-kamfor + NADPH + H+ + O2 (+)-6-ekso-hidroksikamfor + NADP+ + H2O
Ova citohrom P-450 monooksigenaza je izolovana iz Salvia officinalis.
Reference[uredi | uredi kod]
- ↑ Funk, C., Koepp, A.E. and Croteau, R. (1992). „Catabolism of camphor in tissue cultures and leaf disks of common sage (Salvia officinalis)”. Arch. Biochem. Biophys. 294: 306-313. PMID 1550356.
- ↑ Funk, C. and Croteau, R. (1993). „Induction and characterization of a cytochrome P-450-dependent camphor hydroxylase in tissue cultures of common sage (Salvia officinalis)”. Plant Physiol. 101: 1231-1237. PMID 12231778.
Literatura[uredi | uredi kod]
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- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.