Acefilin

Izvor: Wikipedia
Acefilin
(IUPAC) ime
2-(1,3-dimetil-2,6-diokso-purin-7-il)sirćetna kiselina
Klinički podaci
Identifikatori
CAS broj 652-37-9
ATC kod nije dodeljen
PubChem[1][2] 69550
ChemSpider[3] 62754
UNII M494UE2YEP YesY
ChEMBL[4] CHEMBL70246 YesY
Hemijski podaci
Formula C9H10N4O4 
Mol. masa 238,20 g/mol
SMILES eMolekuli & PubHem
Farmakoinformacioni podaci
Trudnoća  ?
Pravni status

Acefilin (acetiloksiteofilin) je stimulansni lek iz ksantinske hemijske klase. On deluje kao antagonist adenozinskog receptora. On se kombinuje sa difenhidraminom u farmaceutskoj pripremi etanautina da bi se poništili njegovi sedativni efekti.[5]

Reference[uredi - уреди]

  1. Li Q, Cheng T, Wang Y, Bryant SH (2010). "PubChem as a public resource for drug discovery.". Drug Discov Today 15 (23-24): 1052–7. doi:10.1016/j.drudis.2010.10.003. PMID 20970519.  edit
  2. Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). "Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities". Annual Reports in Computational Chemistry 4: 217–241. doi:10.1016/S1574-1400(08)00012-1. 
  3. Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). "Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining". J Cheminform 2 (1): 3. doi:10.1186/1758-2946-2-3. PMID 20331846.  edit
  4. Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). "ChEMBL: a large-scale bioactivity database for drug discovery". Nucleic Acids Res 40 (Database issue): D1100–7. doi:10.1093/nar/gkr777. PMID 21948594.  edit
  5. Zuidema, Jan. (1978). Biofarmaceutische en farmacokinetische aspecten van theofylline en acefylline. Thesis (doctoral)--Universiteit van Amsterdam. 

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