TRNK (adenin-N1-)-metiltransferaza
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| TRNK (adenin-N1-)-metiltransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.1.1.36 | ||||||||
| CAS broj | 37257-03-7 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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TRNK (adenin-N1-)-metiltransferaza (EC 2.1.1.36, transfer ribonukleat adeninska 1-metiltransferaza, transfer RNK (adenin-1) metiltransferaza, 1-metiladenin transfer RNK metiltransferaza, adenin-1-metilaza, S-adenozil-L-metionin:tRNK (adenin-1-N-)-metiltransferaza) je enzim sa sistematskim imenom S-adenozil-L-metionin:tRNK (adenin-N1-)-metiltransferaza.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
- S-adenozil-L-metionin + tRNK S-adenozil-L-homocistein + tRNK N1-metiladenin
Enzimi iz različitih izvora su specifični za različite adeninske ostatke u tRNK.
Reference[uredi | uredi kod]
- ↑ Baguley, B.C. and Staehelin, M. (1968). „The specificity of transfer ribonucleic acid methylases from rat liver”. Biochemistry 7: 45-50. PMID 4921283.
- ↑ Björk, G.R. and Svensson, I. (1969). „Studies on microbial RNA. Fractionation of tRNA methylases from Saccharomyces cerevisiae”. Eur. J. Biochem. 9: 207-215. PMID 4896260.
- ↑ Dubois, E.E., Dirheimer, G. and Weil, J.H. (1974). „Methylation of yeast tRNA Asp by enzymes from cytoplasm, chloroplasts and mitochondria of Phaseolus vulgaris”. Biochim. Biophys. Acta 374: 332-341. PMID 4611497.
- ↑ Glick, J.M. and Leboy, P.S. (1977). „Purification and properties of tRNA(adenine-1)-methyltransferase from rat liver”. J. Biol. Chem. 252: 4790-4795. PMID 17605.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.