Sijalatna O-acetilestaraza
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| Sijalatna O-acetilestaraza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.1.1.53 | ||||||||
| CAS broj | 89400-31-7 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Sijalatna O-acetilestaraza (EC 3.1.1.53, N-acetilneuraminatna acetiltransferaza, sijalat 9(4)-O-acetilesteraza, sijalidaza) je enzim sa sistematskim imenom N-acil-O-acetilneuraminat O-acetilhidrolaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- N-acetil-O-acetilneuraminat + H2O N-acetilneuraminat + acetat
Ovaj enzim deluje na slobodne i glikozidno vezane N-acetil- ili N-glikoloil-neuraminske kiseline.
Reference[uredi | uredi kod]
- ↑ Garcia-Sastre, A., Villar, E., Manuguerra, J.C., Hannoun, C. and Cabezas, J.A. (1991). „Activity of influenza C virus O-acetylesterase with O-acetyl-containing compounds”. Biochem. J. 273: 435-441. PMID 1991039.
- ↑ Shukla, A.K. and Schauer, R. (1982). „High performance liquid chromatography of enzymes of sialic acid metabolism”. Hoppe-Seyler's Z. Physiol. Chem. 363: 1039-1040.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.