Serinska racemaza

Izvor: Wikipedia
Serinska racemaza
Crystal structure of serine racemase 3hmk.png
Identifikatori
EC broj 5.1.1.18
CAS broj 77114-08-0
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures

Serinska racemaza (EC 5.1.1.18, SRR) je enzim sa sistematskim imenom serin racemaza.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju

L-serin \rightleftharpoons D-serin

Ovaj enzim sadrži piridoksal fosfat.

Reference[uredi - уреди]

  1. Wolosker, H., Blackshaw, S. and Snyder, S.H. (1999). "Serine racemase: a glial enzyme synthesizing D-serine to regulate glutamate-N-methyl-D-aspartate neurotransmission". Proc. Natl. Acad. Sci. USA 96: 13409–13414. PMID 10557334. 
  2. Wolosker, H., Sheth, K.N., Takahashi, M., Mothet, J.P., Brady, R.O., Jr., Ferris, C.D. and Snyder, S.H. (1999). "Purification of serine racemase: biosynthesis of the neuromodulator D-serine". Proc. Natl. Acad. Sci. USA 96: 721–725. PMID 9892700. 
  3. De Miranda, J., Santoro, A., Engelender, S. and Wolosker, H. (2000). "Human serine racemase: moleular cloning, genomic organization and functional analysis". Gene 256: 183–188. PMID 11054547. 
  4. Foltyn, V.N., Bendikov, I., De Miranda, J., Panizzutti, R., Dumin, E., Shleper, M., Li, P., Toney, M.D., Kartvelishvily, E. and Wolosker, H. (2005). "Serine racemase modulates intracellular D-serine levels through an α,β-elimination activity". J. Biol. Chem. 280: 1754–1763. PMID 15536068. 

Literatura[uredi - уреди]

Spoljašnje veze[uredi - уреди]