Protein-glutamatna metilsteraza
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| Protein-glutamatna metilsteraza | |||||||||
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| Identifikatori | |||||||||
| EC broj | 3.1.1.61 | ||||||||
| CAS broj | 69552-31-4 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Protein-glutamatna metilsteraza (EC 3.1.1.61, metilsteraza specifična za hemotaksu, metil prihvatajući hemotaksni protein metil-esteraza, CheB metilsteraza, metilsteraza CheB, protein metil-esteraza, protein karboksil metilsteraza, PME, protein metilsteraza, protein-L-glutamat-5-O-metil-estar acilhidrolaza) je enzim sa sistematskim imenom protein-L-glutamat-O5-metil-estar acilhidrolaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- protein L-glutamat O5-metil estar + H2O protein L-glutamat + metanol
Ovaj enzim hidrolizuje produkte enzima EC 2.1.1.77 (protein-L-izoaspartat(D-aspartat) O-metiltransferaza), EC 2.1.1.78 (izoorientin 3'-O-metiltransferaza), EC 2.1.1.80 (protein-glutamat O-metiltransferaza) i EC 2.1.1.100 (protein-S-izoprenilcistein O-metiltransferaza).
Reference[uredi | uredi kod]
- ↑ Gagnon, C., Harbour, G. and Camato, R. (1984). „Purification and characterization of protein methylesterase from rat kidney”. J. Biol. Chem. 259: 10212-10215. PMID 6469959.
- ↑ Kehry, M.R., Doak, T.G. and Dahlquist, F.W. (1984). „Stimulus-induced changes in methylesterase activity during chemotaxis in Escherichia coli”. J. Biol. Chem. 259: 11828-11835. PMID 6384215.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.