Katepsin F

Izvor: Wikipedia
Katepsin F
Protein CTSF PDB 1m6d.png
Identifikatori
EC broj 3.4.22.41
CAS broj 65997-74-2
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures

Katepsin F (EC 3.4.22.41, Cathepsin F) je enzim.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju

Ovaj rekombinantni enzim razlaže sintetičke supstrate sa Phe i Leu (u većoj meri nego Val) u P2, sa visokom specifičnošću slično katepsinu L

Katepsin F je lizozomalna cisteinska endopeptidaza iz familije C1 (papainske familije)

Reference[uredi - уреди]

  1. Santamaría, I., Velasco, G., Pendás, A.M., Paz, A. and López-Otín, C. (1999). "Molecular cloning and structural and functional chararcterization of cathepsin F, a new cysteine proteinase of the papain family with a long propeptide domain". J. Biol. Chem. 274: 13800–13809. PMID 10318784. 
  2. Nägler, D.K. Sulea, T. and Ménard, R. (1999). "Full length cDNA of human cathepsin F predicts the presence of a cystatin domain at the N-terminus of the cysteine protease zymogen". Biochem. Biophys. Res. Commun. 257: 313–318. PMID 10198209. 
  3. Wex, T., Levy, B., Wex, H. and Brömme, D. (1999). "Human cathepsins F and W: A new subgroup of cathepsins". Biochem. Biophys. Res. Commun. 259: 401–407. PMID 10362521. 
  4. Wang, B., Shi, G.-P., Yao, P.M., Li, Z., Chapman, H.A. and Brömme, D. (1998). "Human cathepsin F. Molecular cloning, functional expression, tissue localization, and enzymatic characterization". J. Biol. Chem. 273: 32000–32008. PMID 9822672. 

Literatura[uredi - уреди]

Spoljašnje veze[uredi - уреди]