Glutamin—fenilpiruvat transaminaza
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| Glutamin—fenilpiruvat transaminaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.6.1.64 | ||||||||
| CAS broj | 68518-06-9 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Glutamin—fenilpiruvat transaminaza (EC 2.6.1.64, glutaminska transaminaza K, glutamin-fenilpiruvatna aminotransferaza) je enzim sa sistematskim imenom L-glutamin:fenilpiruvat aminotransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- L-glutamin + fenilpiruvat 2-oksoglutaramat + L-fenilalanin
Ovaj enzim je piridoksal-fosfatni protein. L-metionin, L-histidin i L-tirozin mogu da deluju kao donori.
Reference[uredi | uredi kod]
- ↑ Cooper, A.J.L. (1978). „Purification of soluble and mitochondrial glutamine transaminase K from rat kidney. Use of a sensitive assay involving transamination between L-phenylalanine and α-keto-γ-methiolbutyrate”. Anal. Biochem. 89: 451-460. PMID 727444.
- ↑ Cooper, A.J.L. and Meister, A. (1974). „Isolation and properties of a new glutamine transaminase from rat kidney”. J. Biol. Chem. 249: 2554-2561. PMID 4822504.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.