Acetilsalicilatna deacetilaza
Prijeđi na navigaciju
Prijeđi na pretragu
| Acetilsalicilatna deacetilaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.1.1.55 | ||||||||
| CAS broj | 87348-04-7 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Acetilsalicilatna deacetilaza (EC 3.1.1.55, aspirinska esteraza, aspirinska esteraza, acetilsalicilno kiselinska esteraza, aspirinska hidrolaza) je enzim sa sistematskim imenom acetilsalicilat O-acetilhidrolaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
Aktivnost jetrenog citozolnog enzima je najviša na acetil estrima aril alkohola.
Reference[uredi | uredi kod]
- ↑ Ali, B. and Kaur, S. (1983). „Mammalian tissue acetylsalicylic acid esterase(s): identification, distribution and discrimination from other esterases”. J. Pharmacol. Exp. Ther. 226: 589-594. PMID 6875867.
- ↑ Kim, D.-H., Yang, Y.-S. and Jakoby, W.B. (1990). „Aspirin hydrolyzing esterases from rat liver cytosol”. Biochem. Pharmacol. 40: 481-487. PMID 2383281.
- ↑ White, K.N. and Hope, D.B. (1984). „Partial purification and characterization of a microsomal carboxylesterase specific for salicylate esters from guinea-pig liver”. Biochim. Biophys. Acta 785: 138-147. PMID 6704404.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.