Undekaprenil-difosfooligosaharid—protein glikotransferaza
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| Undekaprenil-difosfooligosaharid—protein glikotransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.4.99.19 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Undekaprenil-difosfooligosaharid—protein glikotransferaza (EC 2.4.99.19, PglB) je enzim sa sistematskim imenom tritrans,heptacis-undekaprenil-difosfooligosaharid:protein-L-asparagin N-beta-D-oligosaharidotransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- tritrans,heptacis-undekaprenil difosfooligosaharid + [protein]-L-asparagin tritrans,heptacis-undekaprenil difosfat + glikoprotein sa oligosaharidnim lancom vezanim N-beta-D-glikozilnom vezom za protein L-asparagin
Ovaj bakterijski enzim je izolovan iz Campylobacter jejuni i Campylobacter lari.
Reference[uredi | uredi kod]
- ↑ Maita, N., Nyirenda, J., Igura, M., Kamishikiryo, J. and Kohda, D. (2010). „Comparative structural biology of eubacterial and archaeal oligosaccharyltransferases”. J. Biol. Chem. 285: 4941-4950. PMID 20007322.
- ↑ Lizak, C., Gerber, S., Numao, S., Aebi, M. and Locher, K.P. (2011). „X-ray structure of a bacterial oligosaccharyltransferase”. Nature 474: 350-355. PMID 21677752.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.