Tirozin-estar sulfotransferaza
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| Tirozin-estar sulfotransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.8.2.9 | ||||||||
| CAS broj | 9055-56-5 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Tirozin-estar sulfotransferaza (EC 2.8.2.9, arilna sulfotransferaza IV, L-tirozin metil estarska sulfotransferaza) je enzim sa sistematskim imenom 3'-fosfoadenilil-sulfat:L-tirozin-metil-estar sulfotransferaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- 3'-fosfoadenilil sulfat + L-tirozin metil estar adenozin 3',5'-bisfosfat + L-tirozin metil estar 4-sulfat
Fenoli i organski hidroksilamini mogu da deluju kao akceptori.
Reference[uredi | uredi kod]
- ↑ Duffel, M. and Jakoby, W.B. (1981). „On the mechanism of aryl sulfotransferase”. J. Biol. Chem. 256: 11123-11127. PMID 6945304.
- ↑ Mattock, P. and Jones, J.G. (1970). „Partial purification and properties of an enzyme from rat liver that catalyses the sulphation of L-tyrosyl derivatives”. Biochem. J. 116: 797-803. PMID 5441369.
- ↑ Sekura, R. and Jakoby, W.B. (1981). „Aryl sulfotransferase IV from rat liver”. Arch. Biochem. Biophys. 211: 352-359. PMID 6946725.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.