Ribonukleaza (poli-(U) specifična)
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| Ribonukleaza (poli-(U) specifična) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.1.26.9 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Ribonukleaza (poli-(U) specifična) (EC 3.1.26.9, ribonukleaza (uracil-specifična), uracil-specifična endoribonukleaza, uracil-specifična Rnaza) je enzim.[1] Ovaj enzim katalizuje sledeću hemijsku reakciju
- Endonukleolitičko razlaganje poli(U) do fragmenata završenih 3'-hidroksi i 5'-fosfatnim grupama
Ovaj enzim formira oligonukleotide sa lancom dužine 6 do 12 ostataka.
Reference[uredi | uredi kod]
- ↑ Bachmann, M., Trautmann, F., Messer, R., Zahn, R.K., Meyer zum Büschenfelde, K.H. and Müller, W.E.G. (1983). „Association of a polyuridylate-specific endoribonuclease with small nuclear ribonucleo-proteins which had been isolated by affinity chromatography using antibodies from a patient with systemic lupus erythematosus”. Eur. J. Biochem. 136: 447-451. PMID 6227485.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.