Purin-nukleozid fosforilaza

Izvor: Wikipedia
Purin-nukleozid fosforilaza
Identifikatori
EC broj 2.4.2.1
CAS broj 9030-21-1
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures

Purin-nukleozid fosforilaza (EC 2.4.2.1, inozinska fosforilaza, PNPase, PUNPI, PUNPII, inozin-guanozinska fosforilaza, nukleotidna fosfataza, purin dezoksinukleozidna fosforilaza, purin dezoksiribonukleozidna fosforilaza, purin nukleozidna fosforilaza, purin ribonukleozidna fosforilaza) je enzim sa sistematskim imenom purin-nukleozid:fosfat riboziltransferaza.[1][2][3][4][5][6] Ovaj enzim katalizuje sledeću hemijsku reakciju

purin nukleozid + fosfat \rightleftharpoons purin + alfa-D-riboza 1-fosfat

Specifičnost ovog enzima nije kompletno određena.

Reference[uredi - уреди]

  1. Agarwal, R.P. and Parks, R.E. (1969). "Purine nucleoside phosphorylase from human erythrocytes. IV. Crystallization and some properties". J. Biol. Chem. 244: 644–647. PMID 5768862. 
  2. Friedkin, M. and Kalckar, H. (1961). "Nucleoside phosphorylases". u: Boyer, P.D., Lardy, H. and Myrbäck, K.. The Enzymes. 5 (2nd izd.). New York: Academic Press. str. 237-255. 
  3. Heppel, L.A. and Hilmoe, R.J. (1952). "Phosphorolysis and hydrolysis of purine ribosides from yeast". J. Biol. Chem. 198: 683–694. PMID 12999785. 
  4. Kalckar, H.M. (1947). "The enzymatic synthesis of purine ribosides". J. Biol. Chem. 167: 477–486. 
  5. Saunders, P.P., Wilson, B.A. and Saunders, G.F. (1969). "Purification and comparative properties of a pyrimidine nucleoside phosphorylase from Bacillus stearothermophilus". J. Biol. Chem. 244: 3691–3697. PMID 4978445. 
  6. Tsuboi, K.K. and Hudson, P.B. (1957). "Enzymes of the human erythrocyte. I. Purine nucleoside phosphorylase; isolation procedure". J. Biol. Chem. 224: 879–887. PMID 13405917. 

Literatura[uredi - уреди]

  • Friedkin, M. and Kalckar, H. (1961). "Nucleoside phosphorylases". u: Boyer, P.D., Lardy, H. and Myrbäck, K.. The Enzymes. 5 (2nd izd.). New York: Academic Press. str. 237-255. 

Spoljašnje veze[uredi - уреди]