Protein-fruktozamin 3-kinaza
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| Protein-fruktozamin 3-kinaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.7.1.171 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Protein-fruktozamin 3-kinaza (EC 2.7.1.171, FN3K, fruktosaminska 3-kinaza) je enzim sa sistematskim imenom ATP:(protein)-N6-D-fruktosil-L-lizin 3-fosfotransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
Neenzimatska glikacija je važan faktor u patogenezi diabetičkih komplikacija.
Reference[uredi | uredi kod]
- ↑ Szwergold, B.S., Howell, S. and Beisswenger, P.J. (2001). „Human fructosamine-3-kinase: purification, sequencing, substrate specificity, and evidence of activity in vivo”. Diabetes 50: 2139-2147. PMID 11522682.
- ↑ Delpierre, G., Rider, M.H., Collard, F., Stroobant, V., Vanstapel, F., Santos, H. and Van Schaftingen, E. (2000). „Identification, cloning, and heterologous expression of a mammalian fructosamine-3-kinase”. Diabetes 49: 1627-1634. PMID 11016445.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.