Protein-disulfid reduktaza (glutation)
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| Protein-disulfid reduktaza (glutation) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.8.4.2 | ||||||||
| CAS broj | 9082-53-5 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Protein-disulfid reduktaza (glutation) (EC 1.8.4.2, glutation-insulinska transhidrogenaza, insulinska reduktaza, reduktaza, protein disulfid (glutation), protein disulfidna transhidrogenaza, glutation-protein disulfidna oksidoreduktaza, protein disulfidna reduktaza (glutation), GSH-insulinska transhidrogenaza, enzim protein-disulfid razmene, protein-disulfidna izomeraza/oksidoreduktaza, tiol:protein-disulfid oksidoreduktaza, tiol-protein disulphidna oksidoreduktaza) je enzim sa sistematskim imenom glutation:protein-disulfid oksidoreduktaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju:
- 2 glutation + protein-disulfid glutation-disulfid + protein-ditiol
Ovaj enzim redukuje insulin i neke druge proteine.
Reference[uredi | uredi kod]
- ↑ Katzen, H.M., Tietze, F. and Stetten, D. (1963). „Further studies on the properties of hepatic glutathione-insulin transhydrogenase”. J. Biol. Chem. 238: 1006-1011. PMID 14031343.
- ↑ Kohnert, K.-D., Hahn, H.-J., Zühlke, H., Schmidt, S. and Fiedler, H. (1974). „Breakdown of exogenous insulin by Langerhans islets of the pancreas in vitro”. Biochim. Biophys. Acta 338: 68-77.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.