Piruvat dehidrogenaza (citohrom)
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| Piruvat dehidrogenaza (citohrom) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.2.2.2 | ||||||||
| CAS broj | 9079-84-9 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Piruvat dehidrogenaza (citohrom) (EC 1.2.2.2, piruvatna dehidrogenaza, piruvinska dehidrogenaza, piruvinska (citohrom b1) dehidrogenaza, piruvat:ubihinon-8-oksidoreduktaza, piruvatna oksidaza (nespecifična)) je enzim sa sistematskim imenom piruvat:fericitohrom-b1 oksidoreduktaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju:
- piruvat + fericitohrom b1 +H2O acetat + CO2 + ferocitohrom b1
Ovaj enzim je flavoprotein. Za njegovo dejstvo je neophodan tiamin difosfat.
Reference[uredi | uredi kod]
- ↑ Williams, F.R. and Hager, L.P. (1961). „A crystalline flavin pyruvate oxidase”. J. Biol. Chem. 236: PC36-PC37. PMID 13785427.
- ↑ Koland, J.G. and Gennis, R.B. (1982). „Identification of an active site cysteine residue in Escherichia coli pyruvate oxidase”. J. Biol. Chem. 257: 6023-6027. PMID 7042705.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.