N-acetilneuraminat 4-O-acetiltransferaza
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| N-acetilneuraminat 4-O-acetiltransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.3.1.44 | ||||||||
| CAS broj | 51004-25-2 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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N-acetilneuraminat 4-O-acetiltransferaza (EC 2.3.1.44, sijalatna O-acetiltransferaza) je enzim sa sistematskim imenom acetil-KoA:N-acetilneuraminat 4-O-acetiltransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- acetil-KoA + N-acetilneuraminat KoA + N-acetil-4-O-acetilneuraminat
Slobodni i glikozidno vezani N-acetil- i N-glikolil- neuraminati mogu da deluju kao O-acetil akceptori.
Reference[uredi | uredi kod]
- ↑ Schauer, R. (1970). „Biosynthese von N-Acetyl-O-acetylneuraminsaüren. I. Inkorporation von [14C]Acetate in Schnitte der Unterkieferspeicheldrüse von Rind und Pferd”. Hoppe-Seyler's Z. Physiol. Chem. 351: 595-602. PMID 5446640.
- ↑ Schauer, R. (1970). „Biosynthese von N-Acetyl-O-acetylneuraminsaüren. II. Untersuchungen über Substrat und intracelluläre Lokalisation der Acetyl-coenzym A: N-acetylneuraminat-7- and 8-O-acetyltransferase von Rind”. Hoppe-Seyler's Z. Physiol. Chem. 351: 749-758. PMID 5425947.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.