Mozavaptan

Mozavaptan
(IUPAC) ime
	N-[4-(5-Dimethylamino-2,3,4,5-tetrahydro-1-benzazepine-1-carbonyl)phenyl]-2-methylbenzamide
Klinički podaci
Identifikatori
CAS broj	137975-06-5
ATC kod	nije dodeljen
PubChem	119369
ChemSpider	106618
Hemijski podaci
Formula	C27H29N3O2
Mol. masa	427.53 g/mol
SMILES	eMolekuli & PubHem
InChI
	InChI=1S/C27H29N3O2/c1-19-9-4-5-10-22(19)26(31)28-21-16-14-20(15-17-21)27(32)30-18-8-13-24(29(2)3)23-11-6-7-12-25(23)30/h4-7,9-12,14-17,24H,8,13,18H2,1-3H3,(H,28,31) ; Key: WRNXUQJJCIZICJ-UHFFFAOYSA-N
Farmakoinformacioni podaci
Trudnoća	?
Pravni status	℞ Prescription only
Način primene	Oralno

Mozavaptan (INN) je antagonist vazopresinskog receptora u prodaji od strane kompanije Otsuka. On je odobren u Japanu oktobra 2006. za hiponatremiju (niske nivoe krvnog natrijuma) uzrokovane sindromom neodgovarajućeg izlučivanja antidiuretskog hormona (SIADH) usled tumora koji proizvodi ADH.^[4]^[5]

Literatura[uredi | uredi kod]

↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit
↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.
↑ Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846. edit
↑ H. Spreitzer (November 20, 2006). „Neue Wirkstoffe - Conivaptan” (German). Österreichische Apothekerzeitung (24/2006).
↑ „Prous Science: Molecule of the Month November 2006”.

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