Molibdopterin-sintaza adenililtransferaza
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| Molibdopterin-sintaza adenililtransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.7.7.80 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Molibdopterin-sintaza adenililtransferaza (EC 2.7.7.80, MoeB, adenililtransferaza i sumportransferaza MOCS3) je enzim sa sistematskim imenom ATP:molibdopterin-sintaza adenililtransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- ATP + [molibdopterin-sintaza sumpor-nosilac protein]-Gly-Gly difosfat + [molibdopterin-sintaza sumpor-nosilac protein]-Gly-Gly-AMP
Ovaj enzim adeniliše C-terminus male podjednice molibdopterinske sintaze.
Reference[uredi | uredi kod]
- ↑ Leimkuhler, S., Wuebbens, M.M. and Rajagopalan, K.V. (2001). „Characterization of Escherichia coli MoeB and its involvement in the activation of molybdopterin synthase for the biosynthesis of the molybdenum cofactor”. J. Biol. Chem. 276: 34695-34701. PMID 11463785.
- ↑ Matthies, A., Nimtz, M. and Leimkuhler, S. (2005). „Molybdenum cofactor biosynthesis in humans: identification of a persulfide group in the rhodanese-like domain of MOCS3 by mass spectrometry”. Biochemistry 44: 7912-7920. PMID 15910006.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.