Metilkrotonoil-KoA karboksilaza
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| Metilkrotonoil-KoA karboksilaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 6.4.1.4 | ||||||||
| CAS broj | 9023-95-4 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Metilkrotonoil-KoA karboksilaza (EC 6.4.1.4, metilkrotonil koenzim A karboksilaza, beta-metilkrotonil koenzim A karboksilaza, beta-metilkrotonil KoA karboksilaza, metilkrotonil-KoA karboksilaza) je enzim sa sistematskim imenom 3-metilkrotonoil-KoA:ugljen-dioksid ligaza (formira ADP).[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
Ovaj enzim je biotinilni protein.
Reference[uredi | uredi kod]
- ↑ Knappe, J., Schlegel, H.-G. and Lynen, F. (1961). „Zur biochemischen Funktion des Biotins. I. Die Beteilligung der β-Methyl-crotonyl-Carboxylase an der Bildung von β-Hydroxy-β-methyl-glutaryl-CoA from β-Hydroxy-isovaleryl-CoA”. Biochem. Z. 335: 101-122. PMID 14457200.
- ↑ Lynen, F., Knappe, J., Lorch, E., Jütting, G., Ringelmann, E. and Lachance, J.-P. (1961). „Zur biochemischen Funktion des Biotins. II. Reinigung und Wirkungsweise der β-Methyl-crotonyl-Carboxlase”. Biochem. Z. 335: 123-166. PMID 14467590.
- ↑ Rilling, H.C. and Coon, M.J. (1960). „The enzymatic isomerization of α-methylvinylacetyl coenzyme A and the specificity of a bacterial α-methylcrotonyl coenzyme A carboxylase”. J. Biol. Chem. 235: 3087-3092. PMID 13741692.
- ↑ Vagelos, P. (1971). „Regulation of fatty acid biosynthesis”. Curr. Top. Cell. Regul. 4: 119-166.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.