Metil halid transferaza
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| Metil halid transferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.1.1.165 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Metil halid transferaza (EC 2.1.1.165, MCT, metil hloridna transferaza, S-adenozil-L-metionin:halid/bisulfid metiltransferaza, AtHOL1, AtHOL2, AtHOL3, HMT, S-adenozil-L-metionin:metiltransferaza halidnog jona, SAM:halidni jon metiltransferaza) je enzim sa sistematskim imenom S-adenozilmetionin:jodid metiltransferaza.[1][2][3][4][5][6] Ovaj enzim katalizuje sledeću hemijsku reakciju
- S-adenozil-L-metionin + jodid S-adenozil-L-homocistein + metil jodid
Ovaj enzim doprinosi metil halidnim emisijama iz Arabidopsis.
Reference[uredi | uredi kod]
- ↑ Ni, X. and Hager, L.P. (1999). „Expression of Batis maritima methyl chloride transferase in Escherichia coli”. Proc. Natl. Acad. Sci. USA 96: 3611-3615. PMID 10097085.
- ↑ Saxena, D., Aouad, S., Attieh, J. and Saini, H.S. (1998). „Biochemical characterization of chloromethane emission from the wood-rotting fungus Phellinus pomaceus”. Appl. Environ. Microbiol. 64: 2831-2835. PMID 9687437.
- ↑ Attieh, J.M., Hanson, A.D. and Saini, H.S. (1995). „Purification and characterization of a novel methyltransferase responsible for biosynthesis of halomethanes and methanethiol in Brassica oleracea”. J. Biol. Chem. 270: 9250-9257. PMID 7721844.
- ↑ Itoh, N., Toda, H., Matsuda, M., Negishi, T., Taniguchi, T. and Ohsawa, N. (2009). „Involvement of S-adenosylmethionine-dependent halide/thiol methyltransferase (HTMT) in methyl halide emissions from agricultural plants: isolation and characterization of an HTMT-coding gene from Raphanus sativus (daikon radish)”. BMC Plant Biol. 9: 116-116. PMID 19723322.
- ↑ Ohsawa, N., Tsujita, M., Morikawa, S. and Itoh, N. (2001). „Purification and characterization of a monohalomethane-producing enzyme S-adenosyl-L-methionine: halide ion methyltransferase from a marine microalga, Pavlova pinguis”. Biosci. Biotechnol. Biochem. 65: 2397-2404. PMID 11791711.
- ↑ Nagatoshi, Y.and Nakamura, T. (2007). „Characterization of three halide methyltransferases in Arabidopsis thaliana”. Plant Biotechnol. 24: 503-506.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.