Metalokarboksipeptidaza D
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| Metalokarboksipeptidaza D | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.4.17.22 | ||||||||
| CAS broj | 153967-26-1 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Metalokarboksipeptidaza D (EC 3.4.17.22, karboksipeptidaza D (goveda, ljudi, miševi, pacovi), gp180 (patka)) je enzim.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- Odvajanje C-terminalnog Arg i Lys sa polipeptida
Ovaj enzim se aktivira jonom Co2+.
Reference[uredi | uredi kod]
- ↑ Kuroki, K., Eng, F., Ishikawa, T., Turck, C., Harada, F. and Ganem, D. (1995). „gp180, a host cell glycoprotein that binds duck hepatitis B virus particles, is encoded by a member of the carboxypeptidase gene family”. J. Biol. Chem. 270: 15022-15028. PMID 9525948.
- ↑ Song, L.X. and Fricker, L.D. (1995). „Purification and characterization of carboxypeptidase D, a novel carboxypeptidase E-like enzyme, from bovine pituitary”. J. Biol. Chem. 270: 25007-25013. PMID 7559630.
- ↑ Song, L.X. and Fricker, L.D. (1996). „Tissue distribution and characterization of soluble and membrane-bound forms of metallocarboxypeptidase D”. J. Biol. Chem. 271: 28884-28889. PMID 8910535.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.