Malonat dekarboksilaza holo-(acil-nosilac protein) sintaza
Prijeđi na navigaciju
Prijeđi na pretragu
| Malonat dekarboksilaza holo-(acil-nosilac protein) sintaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.7.7.66 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Malonat dekarboksilaza holo-(acil-nosilac protein) sintaza (EC 2.7.7.66, holo ACP sintaza, 2'-(5-trifosforibozil)-3'-defosfo-KoA:apo ACP 2'-(5-trifosforibozil)-3'-defosfo-KoA transferaza, MdcG, 2'-(5-trifosforibozil)-3'-defosfo-KoA:apo-malonat-dekarboksilaza adenililtransferaza, holo-malonat-dekarboksilaza sintaza) je enzim sa sistematskim imenom 2'-(5-trifosforibozil)-3'-defosfo-KoA:apo-malonat-dekarboksilaza 2'-(5-fosforibozil)-3'-defosfo-KoA-transferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- 2'-(5-trifosforibozil)-3'-defosfo-KoA + malonat dekarboksilaza apo-[acil-nosilac protein] malonat dekarboksilaza holo-[acil-nosilac protein] + difosfat
Delta podjedinica malonat dekarboksilaze služi kao acil-noseći protein.
Reference[uredi | uredi kod]
- ↑ Hoenke, S., Wild, M.R. and Dimroth, P. (2000). „Biosynthesis of triphosphoribosyl-dephospho-coenzyme A, the precursor of the prosthetic group of malonate decarboxylase”. Biochemistry 39: 13223-13232. PMID 11052675.
- ↑ Hoenke, S., Schmid, M. and Dimroth, P. (2000). „Identification of the active site of phosphoribosyl-dephospho-coenzyme A transferase and relationship of the enzyme to an ancient class of nucleotidyltransferases”. Biochemistry 39: 13233-13240. PMID 11052676.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.