Lozilna endopeptidaza
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| Lozilna endopeptidaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.4.21.50 | ||||||||
| CAS broj | 123175-82-6 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Lozilna endopeptidaza (EC 3.4.21.50, Achromobacter proteinaza I, Achromobacter lyticus alkalna proteinaza I, proteaza I, ahromopeptidaza, proteinaza specifična za lizilnu vezu) je enzim.[1][2][3][4][5][6] Ovaj enzim katalizuje sledeću hemijsku reakciju
- Preferentno razlaganje: Lys-, uključujući -Lys-Pro-
Ovaj enzim je izolovan iz Achromobacter lyticus.
Reference[uredi | uredi kod]
- ↑ Masaki, T., Tanabe, M., Nakamura, K. and Soejima, M. (1981). „Studies on a new proteolytic enzyme from Achromobacter lyticus M497-1. I. Purification and some enzymatic properties”. Biochim. Biophys. Acta. 660: 44-50. PMID 6791693.
- ↑ Masaki, T., Fujihasi, T., Nakamura, K. and Soejima, M. (1981). „Studies on a new proteolytic enzyme from Achromobacter lyticus M497-1. II. Specificity and inhibition studies of Achromobacter protease I”. Biochim. Biophys. Acta 660: 51-55. PMID 6168293.
- ↑ Jekel, P.A., Weijer, W.J. and Beintema, J.J. (1983). „Use of endoproteinase Lys-C from Lysobacter enzymogenes in protein sequence analysis”. Anal. Biochem. 134: 347-354. PMID 6359954.
- ↑ Elliott, B.W. and Cohen, C. (1986). „Isolation and characterization of a lysine-specific protease from Pseudomonas aeruginosa”. J. Biol. Chem. 261: 11259-11265. PMID 3090046.
- ↑ Ohara, T., Makino, K., Shinagawa, H., Nakata, A., Norioka, S. and Sakiyama, F. (1989). „Cloning, nucleotide sequence, and expression of Achromobacter protease I gene”. J. Biol. Chem. 264: 20625-2063. PMID 2684982.
- ↑ Tsunasawa, S., Masaki, T., Hirose, M., Soejima, M. and Sakiyama, F. (1989). „The primary structure and structural characteristics of Achromobacter lyticus protease I, a lysine-specific serine protease”. J. Biol. Chem. 264: 3832-3839. PMID 2492988.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.