Laktoilglutationska lijaza
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| Laktoilglutationska lijaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
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| Identifikatori | |||||||||
| EC broj | 4.4.1.5 | ||||||||
| CAS broj | 2605619 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Laktoilglutationska lijaza (EC 4.4.1.5, metilglioksalaza, aldoketomutaza, keton-aldehidna mutaza, glioksilaza I, (R)-S-laktoilglutation metilglioksal-lijaza (izomerizacija)) je enzim sa sistematskim imenom (R)-S-laktoilglutation metilglioksal-lijaza (izomerizacija, formira glutation).[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- (R)-S-laktoilglutation glutation + metilglioksal
Ovaj enzim takođe deluje na 3-fosfoglicerol-glutation.
Reference[uredi | uredi kod]
- ↑ Ekwall, K. and Mannervik, B. (1973). „The stereochemical configuration of the lactoyl group of S-lactoylglutathionine formed by the action of glyoxalase I from porcine erythrocytes and yeast”. Biochim. Biophys. Acta 297: 297-299. PMID 4574550.
- ↑ Racker, E. (1951). „The mechanism of action of glyoxalase”. J. Biol. Chem. 190: 685-696. PMID 14841219.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.