Fosfolipid:diacilglicerol aciltransferaza
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Fosfolipid:diacilglicerol aciltransferaza | |||||||||
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Identifikatori | |||||||||
EC broj | 2.3.1.158 | ||||||||
CAS broj | 288587-47-3 | ||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Fosfolipid:diacilglicerol aciltransferaza (EC 2.3.1.158, PDAT) je enzim sa sistematskim imenom fosfolipid:1,2-diacil-sn-glicerol O-aciltransferaza.[1] Ovaj enzim katalizuje sledeću hemijsku reakciju
- fosfolipid + 1,2-diacil-sn-glicerol lizofosfolipid + triacilglicerol
Ovaj enzim se razlikuje od enzima [[EC 2.3.1.20], diacilglicerol O-aciltransferaze. On sintetiše triacilglicerol koristeći acil-KoA-nezavisni mehanizam.
Reference[uredi | uredi kod]
- ↑ Dahlqvist, A., Stähl, U., Lenman, M., Banas, A., Lee, M., Sandager, L., Ronne, H. and Stymne, S. (2000). „Phospholipid:diacylglycerol acyltransferase: An enzyme that catalyzes the acyl-CoA-independent formation of triacylglycerol in yeast and plants”. Proc. Natl. Acad. Sci. USA 97: 6487-6492. PMID 10829075.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.