Faktor komplementa D
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| Komplementni faktor D | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.4.21.46 | ||||||||
| CAS broj | 37213-56-2 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Komplementni faktor D (EC 3.4.21.46, C3 proaktivatorna konvertaza, esteraza properdinskog faktora D, faktor D, faktor D (komplement)) je enzim.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- Selektivno razlaganje Arg-Lys veze komplemenom faktoru B kad je u kompleksu sa komplementnom potkomponentom C3b ili faktorom kobra venoma
Ovaj enzim je komponenta alternativnog puta komplementne aktivacije.
Reference[uredi | uredi kod]
- ↑ Reid, K.B.M., Johnson, D.M.A., Gagnon, J. and Prohaska, R. (1981). „P'reparation of human factor D of the alternative pathway of complement”. Methods Enzymol. 80: 134-143. PMID 6918766.
- ↑ Müller-Eberhard, H.J. (1988). „Molecular organization and function of the complement system”. Annu. Rev. Biochem. 57: 321-347. PMID 3052276.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.