Dodecenoil-KoA D-izomeraza
Prijeđi na navigaciju
Prijeđi na pretragu
| Dodecenoil-KoA D-izomeraza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 5.3.3.8 | ||||||||
| CAS broj | 62213-29-0 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Dodecenoil-KoA D-izomeraza (EC 5.3.3.8, dodecenoil-KoA Delta-izomeraza, Delta3-cis-Delta2-trans-enoil-KoA izomeraza, acetilen-alenska izomeraza, dodecenoil-KoA Delta-izomeraza, dodecenoil-KoA Delta3-cis-Delta2-trans-izomeraza) je enzim sa sistematskim imenom dodecenoil-KoA (3Z)-(2E)-izomeraza.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
- (3Z)-dodec-3-enoil-KoA (2E)-dodec-2-enoil-KoA
Ovaj enzim takođe katalizuje interkonverziju 3-acetilenskih masnih acil tioestara i (+)-2,3-dienoilnih masnih acil tioestara.
Reference[uredi | uredi kod]
- ↑ Miesowicz, F.M. and Bloch, K. (1979). „Purification of hog liver isomerase. Mechanism of isomerization of 3-alkenyl and 3-alkynyl thioesters”. J. Biol. Chem. 254: 5868-5877. PMID 376522.
- ↑ Stoffel, W., Ditzer, R. and Caesar, H. (1964). „Der Stoffwechsel der ungesättigten Fettsäuren. III. Zur β-Oxydation der Mono- und Polyenfettsäuren. Der Mechanismus der enzymatischen Reaktionen an Δ3cis-Enoyl-CoA-Verbindungen”. Hoppe-Seyler's Z. Physiol. Chem. 339: 167-181. PMID 5830064.
- ↑ Stoffel, W. and Ecker, W. (1979). „Δ3-cis,-Δ2-trans-Enoyl-CoA isomerase from rat liver mitochondria”. Methods Enzymol. 14: 99-105.
- ↑ Stoffel, W. and Grol, M. (1978). „Purification and properties of 3-cis-2-trans-enoyl-CoA isomerase (dodecenoyl-CoA Δ-isomerase) from rat liver mitochondria”. Hoppe-Seyler's Z. Physiol. Chem. 359: 1777-1782. PMID 738702.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.