Dihidroksi kiselinska dehidrataza
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| Dihidroksi kiselinska dehidrataza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 4.2.1.9 | ||||||||
| CAS broj | 9024-32-2 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Dihidroksi kiselinska dehidrataza (EC 4.2.1.9, acetohidroksikiselinska dehidrataza, alfa,beta-dihidroksikiselinska dehidrataza, 2,3-dihidroksiizovaleratna dehidrataza, alfa,beta-dihidroksiizovaleratna dehidrataza, dihidroksi kiselinska dehidraza, DHAD, 2,3-dihidroksi-kiselinska hidrolijaza) je enzim sa sistematskim imenom 2,3-dihidroksi-3-metilbutanoat hidrolijaza (formira 3-metil-2-oksobutanoat).[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- 2,3-dihidroksi-3-metilbutanoat 3-metil-2-oksobutanoat + H2O
Reference[uredi | uredi kod]
- ↑ Kanamori, M. and Wixom, R.L. (1963). „Studies in valine biosynthesis. V. Characteristics of the purified dihydroxyacid dehydratase from spinach leaves”. J. Biol. Chem. 238: 998-1005. PMID 13962154.
- ↑ Myers, J.W. (1961). „Dihydroxy acid dehydrase: an enzyme involved in the biosynthesis of isoleucine and valine”. J. Biol. Chem. 236: 1414-1418. PMID 13727223.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.