Diaminobutirat acetiltransferaza
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| Diaminobutirat acetiltransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.3.1.178 | ||||||||
| CAS broj | 130456-92-7 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Diaminobutirat acetiltransferaza (EC 2.3.1.178, L-2,4-diaminobutiratna acetiltransferaza, L-2,4-diaminobutanoatna acetiltransferaza, EctA, acetiltransferaza diaminobutirne kiseline, DABA acetiltransferaza, 2,4-diaminobutanoatna acetiltransferaza, DAB acetiltransferaza, DABAcT, acetil-KoA:L-2,4-diaminobutanoatna 4-N-acetiltransferaza) je enzim sa sistematskim imenom acetil-KoA:L-2,4-diaminobutanoat N4-acetiltransferaza.[1][2][3][4][5] Ovaj enzim katalizuje sledeću hemijsku reakciju
- acetil-KoA + L-2,4-diaminobutanoat KoA + N4-acetil-L-2,4-diaminobutanoat
Za rad ovog enzima je neophodan jon Na+ ili K+ za maksimalnu aktivnost.
Reference[uredi | uredi kod]
- ↑ Peters, P., Galinski, E.A. and Truper, H.G. (1990). „The biosynthesis of ectoine”. FEMS Microbiol. Lett. 71: 157-162.
- ↑ Ono, H., Sawada, K., Khunajakr, N., Tao, T., Yamamoto, M., Hiramoto, M., Shinmyo, A., Takano, M. and Murooka, Y. (1999). „Characterization of biosynthetic enzymes for ectoine as a compatible solute in a moderately halophilic eubacterium, Halomonas elongata”. J. Bacteriol. 181: 91-99. PMID 9864317.
- ↑ Reshetnikov, A.S., Mustakhimov, I.I., Khmelenina, V.N. and Trotsenko, Y.A. (2005). „Cloning, purification, and characterization of diaminobutyrate acetyltransferase from the halotolerant methanotroph Methylomicrobium alcaliphilum 20Z”. Biochemistry (Mosc) 70: 878-883. PMID 16212543.
- ↑ Kuhlmann, A.U. and Bremer, E. (2002). „Osmotically regulated synthesis of the compatible solute ectoine in Bacillus pasteurii and related Bacillus spp”. Appl. Environ. Microbiol. 68: 772-783. PMID 11823218.
- ↑ Louis, P. and Galinski, E.A. (1997). „Characterization of genes for the biosynthesis of the compatible solute ectoine from Marinococcus halophilus and osmoregulated expression in Escherichia coli”. Microbiology 143: 1141-1149. PMID 9141677.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.