DTDP-4-amino-4,6-didezoksi-D-glukoza aciltransferaza
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| DTDP-4-amino-4,6-didezoksi-D-glukoza aciltransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.3.1.209 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
DTDP-4-amino-4,6-didezoksi-D-glukoza aciltransferaza (EC 2.3.1.209, VioB) je enzim sa sistematskim imenom acetil-KoA:dTDP-4-amino-4,6-didezoksi-alfa-D-glukoza N-acetiltransferaza.[1] Ovaj enzim katalizuje sledeću hemijsku reakciju
- acetil-KoA + dTDP-4-amino-4,6-didezoksi-alfa-D-glukoza KoA + dTDP-4-acetamido-4,6-didezoksi-alfa-D-glukoza
Neaktivirani produkt, 4-acetamido-4,6-didezoksi-alfa-D-glukoza, je deo O antigena Shigella dysenteriae tipa 7 i Escherichia coli O7.
Reference[uredi | uredi kod]
- ↑ Wang, Y., Xu, Y., Perepelov, A.V., Qi, Y., Knirel, Y.A., Wang, L. and Feng, L. (2007). „Biochemical characterization of dTDP-D-Qui4N and dTDP-D-Qui4NAc biosynthetic pathways in Shigella dysenteriae type 7 and Escherichia coli O7”. J. Bacteriol. 189: 8626-8635. PMID 17905981.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.