Anserin

Izvor: Wikipedia
Anserin
Anserine.png
IUPAC ime
Drugi nazivi beta-Alanil-N(pi)-metil-L-histidin
Identifikacija
CAS registarski broj 584-85-0 YesY
PubChem[1][2] 112072
ChemSpider[3] 100482 YesY
KEGG[4] C01262
ChEBI 18323
ChEMBL[5] CHEMBL448301 YesY
Jmol-3D slike Slika 1
Svojstva
Molekulska formula C10H16N4O3
Molarna masa 240,25904

 YesY (šta je ovo?)   (verifikuj)

Ukoliko nije drugačije napomenuto, podaci se odnose na standardno stanje (25 °C, 100 kPa) materijala

Infobox references

Anserin (beta-alanil-N-metilhistidin) je dipeptid prisutan u skeletalnim mišićima i mozgu sisara[6] and birds.

On je antioksidans (oko 5 puta jači od karnozina). pKa vrednost imidazolnog prstena histidina u anserinu je 7,04. Iz tog razloga je arserin efektivan bufer na fiziolopkom pH.[7]

Reference[uredi - уреди]

  1. Li Q, Cheng T, Wang Y, Bryant SH (2010). "PubChem as a public resource for drug discovery.". Drug Discov Today 15 (23-24): 1052–7. doi:10.1016/j.drudis.2010.10.003. PMID 20970519.  edit
  2. Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). "Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities". Annual Reports in Computational Chemistry 4: 217–241. doi:10.1016/S1574-1400(08)00012-1. 
  3. Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). "Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining". J Cheminform 2 (1): 3. doi:10.1186/1758-2946-2-3. PMID 20331846.  edit
  4. Joanne Wixon, Douglas Kell (2000). "Website Review: The Kyoto Encyclopedia of Genes and Genomes — KEGG". Yeast 17 (1): 48–55. doi:10.1002/(SICI)1097-0061(200004)17:1<48::AID-YEA2>3.0.CO;2-H. 
  5. Gaulton A, Bellis LJ, Bento AP, Chambers J, Davies M, Hersey A, Light Y, McGlinchey S, Michalovich D, Al-Lazikani B, Overington JP. (2012). "ChEMBL: a large-scale bioactivity database for drug discovery". Nucleic Acids Res 40 (Database issue): D1100–7. doi:10.1093/nar/gkr777. PMID 21948594.  edit
  6. Quantitative studies of carnosine and anserine in mammalian muscle. 1938 (pdf)
  7. Biochemistry, Garrett & Grisham

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