Alkan 1-monooksigenaza
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| Alkan 1-monooksigenaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.14.15.3 | ||||||||
| CAS broj | 9059-16-9 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Alkan 1-monooksigenaza (EC 1.14.15.3, alkanska 1-hidroksilaza, omega-hidroksilaza, masna kiselina omega-hidroksilaza, alkanska monooksigenaza, 1-hidroksilaza, alkanska hidroksilaza) je enzim sa sistematskim imenom alkan,redukovani-rubredoksin:kiseonik 1-oksidoreduktaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakcijuČ
- oktan + redukovani rubredoksin + O2 1-oktanol + oksidovani rubredoksin + H2O
Neki enzimi u ovoj grupi su hem-tiolatni proteini (P-450). Oni takođe hidroksilišu masne kiseline u omega-poziciji.
Reference[uredi | uredi kod]
- ↑ Cardini, G. and Jurtshuk, P. (1970). „The enzymatic hydroxylation of n-octane by Corynebacterium sp. strain 7E1C”. J. Biol. Chem. 245: 2789-2796. PMID 4317878.
- ↑ McKenna, E.J. and Coon, M.J. (1970). „Enzymatic ω-oxidation. IV. Purification and properties of the ω-hydroxylase of Pseudomonas oleovorans”. J. Biol. Chem. 245: 3882-3889. PMID 4395379.
- ↑ Peterson, J.A., Kusunose, M., Kusunose, E. and Coon, M.J. (1967). „Enzymatic ω-oxidation. II. Function of rubredoxin as the electron carrier in ω-hydroxylation”. J. Biol. Chem. 242: 4334-4340. PMID 4294330.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.