Adenozilhomocisteinaza
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| Adenozilhomocisteinaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
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| Tetramer adenozilhomocisteinaze (čovjek) | |||||||||
| Identifikatori | |||||||||
| EC broj | 3.3.1.1 | ||||||||
| CAS broj | 9025-54-1 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Adenozilhomocisteinaza (EC 3.3.1.1, S-adenozilhomocisteinska sintaza, S-adenozilhomocisteinska hidrolaza, adenozilhomocisteinska hidrolaza, S-adenozilhomocisteinaza, SAHaza) je enzim sa sistematskim imenom S-adenozil-L-homocisteinska hidrolaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- S-adenozil-L-homocistein + H2O L-homocistein + adenozin
Ovaj enzim sadrži jedan vezani NAD+ molekul po podjedinici.
Reference[uredi | uredi kod]
- ↑ de la Haba, G. and Cantoni, G.L. (1959). „The enzymatic synthesis of S-adenosyl-L-homocysteine from adenosine and homocysteine”. J. Biol. Chem. 234: 603-608. PMID 13641268.
- ↑ Palmer, J.L. and Abeles, R.H. (1979). „The mechanism of action of S-adenosylhomocysteinase”. J. Biol. Chem. 254: 1217-1226. PMID 762125.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.