Adenain

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Adenain
Identifikatori
EC broj 3.4.22.39
CAS broj 369652-03-9
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures

Adenain (EC 3.4.22.39, Adenain) je enzim.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju

Razlaganje proteina adenovirusa i ćelija domaćina na dva mesta konsenzusa: -Yaa-Xaa-Gly-Gly-Xaa- i -Yaa-Xaa-Gly-Xaa-Gly- (pri čemu je Yaa: Met, Ile ili Leu, i Xaa je bilo koja aminokiselina)

Ovu cisteinsku endopeptidazu kodiraju adenovirusi.

Reference[uredi - уреди]

  1. Webster, A., Hay, R.T. and Kemp, G. (1993). "The adenovirus protease is activated by a virus-coded disulphide-linked peptide". Cell 72: 274–275. PMID 8422686. 
  2. Ding, J.Z., McGrath, W.J., Sweet, R.M. and Mangel, W.F. (1996). "Crystal structure of the human adenovirus proteinase with its 11 residue cofactor". EMBO J. 15: 1778–1783. PMID 8617222. 
  3. Weber, J.M. (1998). "Adenovirus protease". u: Barrett, A.J., Rawlings, N.D. and Woessner, J.F.. Handbook of Proteolytic Enzymes. London: Academic Press. str. 741-743. 

Literatura[uredi - уреди]

  • Weber, J.M. (1998). "Adenovirus protease". u: Barrett, A.J., Rawlings, N.D. and Woessner, J.F.. Handbook of Proteolytic Enzymes. London: Academic Press. str. 741-743. 

Vanjske veze[uredi - уреди]