5-Metiltioriboza-1-fosfatna izomeraza
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5-Metiltioriboza-1-fosfatna izomeraza | |||||||||
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Identifikatori | |||||||||
EC broj | 5.3.1.23 | ||||||||
CAS broj | 91608-95-6 | ||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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5-Metiltioriboza-1-fosfatna izomeraza (EC 5.3.1.23, metiltioriboza 1-fosfat izomeraza, 1-PMTR izomeraza, 5-metiltio-5-dezoksi-D-riboza-1-fosfat ketol-izomeraza, S-metil-5-tio-5-dezoksi-D-riboza-1-fosfat ketol-izomeraza, S-metil-5-tio-5-dezoksi-D-riboza-1-fosfat aldoza-ketose-izomeraza, 1-fosfo-5'-S-metiltioriboza izomeraza, S-metil-5-tio-D-riboza-1-fosfat aldoza-ketoza-izomeraza) je enzim sa sistematskim imenom S-metil-5-tio-alfa-D-riboza-1-fosfat aldoza-ketoza-izomeraza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- S-metil-5-tio-alfa-D-riboza 1-fosfat S-metil-5-tio-D-ribuloza 1-fosfat
Reference[uredi | uredi kod]
- ↑ Ghoda, L.Y., Savarese, T.M., Dexter, D.L., Parks, R.E., Jr., Trackman, P.C. and Abeles, R.H. (1984). „Characterization of a defect in the pathway for converting 5′-deoxy-5′-methylthioadenosine to methionine in a subline of a cultured heterogeneous human colon carcinoma”. J. Biol. Chem. 259: 6715-6719. PMID 6725268.
- ↑ Trackman, P.C. and Abeles, R.H. (1983). „Methionine synthesis from 5′-S-methylthioadenosine. Resolution of enzyme activities and identification of 1-phospho-5-S-methylthioribulose”. J. Biol. Chem. 258: 6717-6720. PMID 6853500.
- ↑ Furfine, E.S. and Abeles, R.H. (1988). „Intermediates in the conversion of 5′-S-methylthioadenosine to methionine in Klebsiella pneumoniae”. J. Biol. Chem. 263: 9598-9606. PMID 2838472.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.