2-Piron-4,6-dikarboksilatna laktonaza
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| 2-Piron-4,6-dikarboksilatna laktonaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.1.1.57 | ||||||||
| CAS broj | 84177-55-9 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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2-Piron-4,6-dikarboksilatna laktonaza (EC 3.1.1.57, 2-piron-4,6-dikarboksilatna hidrolaza, 2-piron-4,6-dikarboksilatna laktonohidrolaza) je enzim sa sistematskim imenom 2-okso-2H-piran-4,6-dikarboksilat laktonohidrolaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
- 2-okso-2H-piran-4,6-dikarboksilat + H2O (1E)-4-oksobut-1-en-1,2,4-trikarboksilat
Najverovatniji produkt je keto-forma 4-oksalomesakonata.
Reference[uredi | uredi kod]
- ↑ Kersten, P.J., Dagley, S., Whittaker, J.W., Arciero, D.M. and Lipscomb, J.D. (1982). „2-Pyrone-4,6-dicarboxylic acid, a catabolite of gallic acids in Pseudomonas species”. J. Bacteriol. 152: 1154-1162. PMID 7142106.
- ↑ Maruyama, K. (1983). „Purification and properties of 2-pyrone-4,6-dicarboxylate hydrolase”. J. Biochem. (Tokyo) 93: 557-565. PMID 6841353.
- ↑ Nogales, J., Canales, A., Jimenez-Barbero, J., Serra, B., Pingarron, J.M., Garcia, J.L. and Diaz, E. (2011). „Unravelling the gallic acid degradation pathway in bacteria: the gal cluster from Pseudomonas putida”. Mol. Microbiol. 79: 359-374. PMID 21219457.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.