2-Acilglicerofosfoholin O-aciltransferaza
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2-Acilglicerofosfoholin O-aciltransferaza | |||||||||
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Identifikatori | |||||||||
EC broj | 2.3.1.62 | ||||||||
CAS broj | 64295-73-4 | ||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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2-Acilglicerofosfoholin O-aciltransferaza (EC 2.3.1.62, 2-acilglicerol-3-fosforilholinska aciltransferaza, 2-acilglicerofosfoholinska aciltransferaza) je enzim sa sistematskim imenom acil-KoA:2-acil-sn-glicero-3-fosfoholin O-aciltransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
- acil-KoA + 2-acil-sn-glicero-3-fosfoholin KoA + fosfatidilholin
Reference[uredi | uredi kod]
- ↑ Lands, W.E.M. and Hart, P. (1965). „Metabolism of glycerolipids. VI. Specificities of acyl coenzyme A:phospholipid acyltransferases”. J. Biol. Chem. 240: 1905-1911. PMID 14299609.
- ↑ van den Bosch, H., van Golde, L.M.G., Slotboom, A.J. and van Deenen, L.L.M. (1968). „The acylation of isomeric monoacyl phosphatidylcholines”. Biochim. Biophys. Acta 152: 694-703. PMID 5660084.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.