(S)-limonen 6-monooksigenaza
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| (S)-limonen 6-monooksigenaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.14.13.48 | ||||||||
| CAS broj | 138066-93-0 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
(S)-limonen 6-monooksigenaza (EC 1.14.13.48, (-)-limonenska 6-hidroksilaza, (-)-limonenska 6-monooksigenaza, (-)-limonen,NADPH:kiseonik oksidoreduktaza (6-hidroksilacija)) je enzim sa sistematskim imenom (S)-limonen,NADPH:kiseonik oksidoreduktaza (6-hidroksilacija).[1] Ovaj enzim katalizuje sledeću hemijsku reakciju
- (S)-limonen + NADPH + H+ + O2 (-)-trans-karveol + NADP+ +H2O
Ovaj enzim ima visoku specifičnost. On može da koristi NADH umesto NADPH, ali je brzina reakcije znatno niža. On je hem-tiolatni protein (P-450).
Reference[uredi | uredi kod]
- ↑ Karp, F., Mihaliak, C.A., Harris, J.L. and Croteau, R. (1990). „Monoterpene biosynthesis: specificity of the hydroxylations of (-)-limonene by enzyme preparations from peppermint (Mentha piperita), spearmint (Mentha spicata), and perilla (Perilla frutescens) leaves”. Arch. Biochem. Biophys. 276: 219-226. PMID 2297225.
Literatura[uredi | uredi kod]
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.